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Usual Dose: Losartan potassium 50 mg/hydrochlorothiazide 12.5 mg once daily. The dose may be increase, if necessary, to 100 mg/25 mg daily as a single dose or in 2 divided doses.
Elderly >75 years, Patients with Moderate to Severe Renal Impairment [Creatinine Clearance (CrCl) <20 mL/min] or Intravascular Fluid Depletion: Initial Dose: 25 mg once daily.
